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The killer immunoglobulin-like receptor KIR3DL1 combination with HLA-Bw4 is protective against multiple sclerosis in African Americans

We investigated the role of the KIR loci and their HLA class I ligands in a large cohort of African American MS patients (N=907) and controls (N=1456). No significant differences in carrier frequencies for any KIR locus or haplotype were observed between cases and controls. However, examination of K...

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Detalles Bibliográficos
Autores principales: Hollenbach, Jill A., Pando, Marcelo J., Caillier, Stacy J., Gourraud, Pierre-Antoine, Oksenberg, Jorge R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105680/
https://www.ncbi.nlm.nih.gov/pubmed/26866467
http://dx.doi.org/10.1038/gene.2016.5