Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase

Mutations that cause genome instability are considered important predisposing events that contribute to initiation and progression of cancer. Genome instability arises either due to defects in genes that cause an increased mutation rate (mutator phenotype), or defects in genes that cause chromosome...

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Detalles Bibliográficos
Autores principales: Ang, J. Sidney, Duffy, Supipi, Segovia, Romulo, Stirling, Peter C., Hieter, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105872/
https://www.ncbi.nlm.nih.gov/pubmed/27585847
http://dx.doi.org/10.1534/genetics.116.192211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105872/
https://www.ncbi.nlm.nih.gov/pubmed/27585847
http://dx.doi.org/10.1534/genetics.116.192211

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