Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation

The Rac1 GTPase plays key roles in cytoskeletal organization, cell motility and a variety of physiological and disease-linked responses. Wild type Rac1 signaling entails dissociation of the GTPase from cytosolic Rac1-Rho GDP dissociation inhibitor (GDI) complexes, translocation to membranes, activat...

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Detalles Bibliográficos
Autores principales: Castro-Castro, Antonio, Muriel, Olivia, del Pozo, Miguel A., Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105943/
https://www.ncbi.nlm.nih.gov/pubmed/27835684
http://dx.doi.org/10.1371/journal.pone.0166715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105943/
https://www.ncbi.nlm.nih.gov/pubmed/27835684
http://dx.doi.org/10.1371/journal.pone.0166715

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