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Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation

The Rac1 GTPase plays key roles in cytoskeletal organization, cell motility and a variety of physiological and disease-linked responses. Wild type Rac1 signaling entails dissociation of the GTPase from cytosolic Rac1-Rho GDP dissociation inhibitor (GDI) complexes, translocation to membranes, activat...

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Detalles Bibliográficos
Autores principales:	Castro-Castro, Antonio, Muriel, Olivia, del Pozo, Miguel A., Bustelo, Xosé R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105943/ https://www.ncbi.nlm.nih.gov/pubmed/27835684 http://dx.doi.org/10.1371/journal.pone.0166715

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