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MTV, an ssDNA Protecting Complex Essential for Transposon-Based Telomere Maintenance in Drosophila

Multiple complexes protect telomeres. In telomerase-maintained organisms, Shelterin related complexes occupy the duplex region while the CST and Tpp1-Pot1 complexes bind the single stranded overhang of telomeres. Drosophila uses a transposon-based mechanism for end protection. We showed that the HOA...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhang, Liang, Tang, Xiaona, Bhardwaj, Shilpa R., Ji, Jingyun, Rong, Yikang S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105952/
https://www.ncbi.nlm.nih.gov/pubmed/27835648
http://dx.doi.org/10.1371/journal.pgen.1006435