DNA Methylation-Mediated Downregulation of DEFB1 in Prostate Cancer Cells

Epigenetic aberrations play crucial roles in prostate cancer (PCa) development and progression. The DEFB1 gene, which encodes human ß-defensin-1 (HBD-1), contributes to innate immune responses and functions as a potential tumor suppressor in urological cancers. We investigated whether differential D...

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Detalles Bibliográficos
Autores principales: Lee, Jaehyouk, Han, Jun Hyun, Jang, Ara, Kim, Jin Wook, Hong, Soon Auck, Myung, Soon Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105953/
https://www.ncbi.nlm.nih.gov/pubmed/27835705
http://dx.doi.org/10.1371/journal.pone.0166664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105953/
https://www.ncbi.nlm.nih.gov/pubmed/27835705
http://dx.doi.org/10.1371/journal.pone.0166664

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