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The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in Hepatocellular Carcinoma Cells

Reprogrammed metabolism and redox homeostasis are potential targets of cancer therapy. Our previous study demonstrated that the kidney form of glutaminase (GLS1) is highly expressed in hepatocellular carcinoma (HCC) cells and can be used as a target for effective anticancer therapy. Dihydroartemisin...

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Detalles Bibliográficos
Autores principales: Wang, Diancheng, Meng, Gang, Zheng, Meihong, Zhang, Yonghui, Chen, Aiping, Wu, Junhua, Wei, Jiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105986/
https://www.ncbi.nlm.nih.gov/pubmed/27835669
http://dx.doi.org/10.1371/journal.pone.0166423