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PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases

Susceptibility loci identified by GWAS generally account for a limited fraction of heritability. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limited practical use. Many methods have been developed to overcome these limitations by incorp...

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Detalles Bibliográficos
Autores principales: Ayati, Marzieh, Koyutürk, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105987/
https://www.ncbi.nlm.nih.gov/pubmed/27835645
http://dx.doi.org/10.1371/journal.pcbi.1005195