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Mass Spectrometry Based Metabolomics Comparison of Liver Grafts from Donors after Circulatory Death (DCD) and Donors after Brain Death (DBD) Used in Human Orthotopic Liver Transplantation

Use of marginal liver grafts, especially those from donors after circulatory death (DCD), has been considered as a solution to organ shortage. Inferior outcomes have been attributed to donor warm ischaemic damage in these DCD organs. Here we sought to profile the metabolic mechanisms underpinning do...

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Detalles Bibliográficos
Autores principales: Hrydziuszko, Olga, Perera, M. Thamara P. R., Laing, Richard, Kirwan, Jennifer, Silva, Michael A., Richards, Douglas A., Murphy, Nick, Mirza, Darius F., Viant, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105997/
https://www.ncbi.nlm.nih.gov/pubmed/27835640
http://dx.doi.org/10.1371/journal.pone.0165884