Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21

Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression levels of ORMDL3, GSDMB and ZPBP2 genes. Remarkably, ORMDL3 has been shown t...

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Detalles Bibliográficos
Autores principales: Carreras-Sureda, Amado, Rubio-Moscardo, Fanny, Olvera, Alex, Argilaguet, Jordi, Kiefer, Kerstin, Mothe, Beatriz, Meyerhans, Andreas, Brander, Christian, Vicente, Rubén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106028/
https://www.ncbi.nlm.nih.gov/pubmed/27835674
http://dx.doi.org/10.1371/journal.pone.0166414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106028/
https://www.ncbi.nlm.nih.gov/pubmed/27835674
http://dx.doi.org/10.1371/journal.pone.0166414

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