Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues

Understanding the genetic architecture of gene expression traits is key to elucidating the underlying mechanisms of complex traits. Here, for the first time, we perform a systematic survey of the heritability and the distribution of effect sizes across all representative tissues in the human body. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Wheeler, Heather E., Shah, Kaanan P., Brenner, Jonathon, Garcia, Tzintzuni, Aquino-Michaels, Keston, Cox, Nancy J., Nicolae, Dan L., Im, Hae Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106030/
https://www.ncbi.nlm.nih.gov/pubmed/27835642
http://dx.doi.org/10.1371/journal.pgen.1006423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106030/
https://www.ncbi.nlm.nih.gov/pubmed/27835642
http://dx.doi.org/10.1371/journal.pgen.1006423

Ejemplares similares