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Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues
Understanding the genetic architecture of gene expression traits is key to elucidating the underlying mechanisms of complex traits. Here, for the first time, we perform a systematic survey of the heritability and the distribution of effect sizes across all representative tissues in the human body. W...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106030/ https://www.ncbi.nlm.nih.gov/pubmed/27835642 http://dx.doi.org/10.1371/journal.pgen.1006423 |