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A Dual Color Immunohistochemistry Assay for Measurement of Cereblon in Multiple Myeloma Patient Samples

Clinical interest in the measurement of Cereblon (CRBN), the primary target of the IMiDs immunomodulatory drugs lenalidomide and pomalidomide, has been fueled by its essential requirement for antitumor or immunomodulatory activity of both drugs in multiple myeloma (MM). However, limited analyses of...

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Detalles Bibliográficos
Autores principales: Ren, Yan, Wang, Maria, Couto, Suzana, Hansel, Donna E., Miller, Karen, Lopez-Girona, Antonia, Bjorklund, Chad C., Gandhi, Anita K., Thakurta, Anjan, Chopra, Rajesh, Breider, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106091/
https://www.ncbi.nlm.nih.gov/pubmed/26186254
http://dx.doi.org/10.1097/PAI.0000000000000246