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Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model

BACKGROUND: Studies have suggested that histone modification has a positive impact on various aspects associated with the progression of COPD. Histone deacetylase 2 (HDAC2) suppresses proinflammatory gene expression through deacetylation of core histones. OBJECTIVE: To investigate the effect of hist...

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Detalles Bibliográficos
Autores principales: Gan, Lixing, Li, Chengye, Wang, Jian, Guo, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106221/
https://www.ncbi.nlm.nih.gov/pubmed/27853364
http://dx.doi.org/10.2147/COPD.S113978