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Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model
BACKGROUND: Studies have suggested that histone modification has a positive impact on various aspects associated with the progression of COPD. Histone deacetylase 2 (HDAC2) suppresses proinflammatory gene expression through deacetylation of core histones. OBJECTIVE: To investigate the effect of hist...
Autores principales: | Gan, Lixing, Li, Chengye, Wang, Jian, Guo, Xuejun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106221/ https://www.ncbi.nlm.nih.gov/pubmed/27853364 http://dx.doi.org/10.2147/COPD.S113978 |
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