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Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer
PURPOSE: MicroRNAs (miRNAs) are noncoding RNAs that play roles as tumor suppressors or oncogenes by regulating the expression of target genes via binding to seed-match sequences. Polymorphisms in the miRNA-binding site of a target gene can alter miRNA binding and potentially affect the risk of cance...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106228/ https://www.ncbi.nlm.nih.gov/pubmed/27853382 http://dx.doi.org/10.2147/OTT.S108787 |