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Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer

PURPOSE: MicroRNAs (miRNAs) are noncoding RNAs that play roles as tumor suppressors or oncogenes by regulating the expression of target genes via binding to seed-match sequences. Polymorphisms in the miRNA-binding site of a target gene can alter miRNA binding and potentially affect the risk of cance...

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Detalles Bibliográficos
Autores principales:	Lee, Ah-Reum, Park, Jongkeun, Jung, Keum Ji, Jee, Sun Ha, Kim-Yoon, Sungjoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106228/ https://www.ncbi.nlm.nih.gov/pubmed/27853382 http://dx.doi.org/10.2147/OTT.S108787

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