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Apoptotic neuron-secreted HN12 inhibits cell apoptosis in Hirschsprung’s disease

Perturbation in apoptosis can lead to Hirschsprung’s disease (HSCR), which is a genetic disorder of neural crest development. It is believed that long noncoding RNAs (lncRNAs) play a role in the progression of HSCR. This study shows that apoptotic neurons can suppress apoptosis of nonapoptotic cells...

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Detalles Bibliográficos
Autores principales: Du, Chunxia, Xie, Hua, Zang, Rujin, Shen, Ziyang, Li, Hongxing, Chen, Pingfa, Xu, Xiaoqun, Xia, Yankai, Tang, Weibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106231/
https://www.ncbi.nlm.nih.gov/pubmed/27853370
http://dx.doi.org/10.2147/IJN.S114838