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CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State
Poly(A) tail length and mRNA deadenylation play important roles in gene regulation. However, how they regulate embryonic development and pluripotent cell fate is not fully understood. Here we present evidence that CNOT3-dependent mRNA deadenylation governs the pluripotent state. We show that CNOT3,...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106518/ https://www.ncbi.nlm.nih.gov/pubmed/27746116 http://dx.doi.org/10.1016/j.stemcr.2016.09.007 |