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CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State

Poly(A) tail length and mRNA deadenylation play important roles in gene regulation. However, how they regulate embryonic development and pluripotent cell fate is not fully understood. Here we present evidence that CNOT3-dependent mRNA deadenylation governs the pluripotent state. We show that CNOT3,...

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Detalles Bibliográficos
Autores principales:	Zheng, Xiaofeng, Yang, Pengyi, Lackford, Brad, Bennett, Brian D., Wang, Li, Li, Hui, Wang, Yu, Miao, Yiliang, Foley, Julie F., Fargo, David C., Jin, Ying, Williams, Carmen J., Jothi, Raja, Hu, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106518/ https://www.ncbi.nlm.nih.gov/pubmed/27746116 http://dx.doi.org/10.1016/j.stemcr.2016.09.007

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