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Mathematical modelling of angiogenesis using continuous cell-based models

In this work, we develop a mathematical formalism based on a 3D in vitro model that is used to simulate the early stages of angiogenesis. The model treats cells as individual entities that are migrating as a result of chemotaxis and durotaxis. The phenotypes used here are endothelial cells that can...

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Detalles Bibliográficos
Autores principales: Bookholt, F. D., Monsuur, H. N., Gibbs, S., Vermolen, F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106520/
https://www.ncbi.nlm.nih.gov/pubmed/27037954
http://dx.doi.org/10.1007/s10237-016-0784-3