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Rare SOX2(+) Airway Progenitor Cells Generate KRT5(+) Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection

Recent studies have implicated keratin 5 (KRT5)(+) cells in repopulation of damaged lung tissue following severe H1N1 influenza virus infection. However, the origins of the cells repopulating the injured alveolar region remain controversial. We sought to determine the cellular dynamics of lung repai...

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Detalles Bibliográficos
Autores principales: Ray, Samriddha, Chiba, Norika, Yao, Changfu, Guan, Xiangrong, McConnell, Alicia M., Brockway, Brian, Que, Loretta, McQualter, Jonathan L., Stripp, Barry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106521/
https://www.ncbi.nlm.nih.gov/pubmed/27773701
http://dx.doi.org/10.1016/j.stemcr.2016.09.010