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Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming

Pro-neural transcription factors and small molecules can induce the reprogramming of fibroblasts into functional neurons; however, the immediate-early molecular events that catalyze this conversion have not been well defined. We previously demonstrated that neurogenin 2 (NEUROG2), forskolin (F), and...

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Detalles Bibliográficos
Autores principales: Smith, Derek K., Yang, Jianjing, Liu, Meng-Lu, Zhang, Chun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106529/
https://www.ncbi.nlm.nih.gov/pubmed/28157484
http://dx.doi.org/10.1016/j.stemcr.2016.09.013