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Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency
Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer (DE) and proximal enhancer (PE), which differentially control Oct4 expression in a cell-type-specific and stage-specific manner. Here, we gener...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106531/ https://www.ncbi.nlm.nih.gov/pubmed/28157483 http://dx.doi.org/10.1016/j.stemcr.2016.09.012 |