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Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency

Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer (DE) and proximal enhancer (PE), which differentially control Oct4 expression in a cell-type-specific and stage-specific manner. Here, we gener...

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Detalles Bibliográficos
Autores principales:	Choi, Hyun Woo, Joo, Jin Young, Hong, Yean Ju, Kim, Jong Soo, Song, Hyuk, Lee, Jeong Woong, Wu, Guangming, Schöler, Hans R., Do, Jeong Tae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106531/ https://www.ncbi.nlm.nih.gov/pubmed/28157483 http://dx.doi.org/10.1016/j.stemcr.2016.09.012

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