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One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation

BACKGROUND: The ability to transform normal human cells into cancer cells with the introduction of defined genetic alterations is a valuable method for understanding the mechanisms of oncogenesis. Easy establishment of immortalized but non-transformed human cells from various tissues would facilitat...

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Detalles Bibliográficos
Autores principales: Smith, Jordan L., Lee, Liam C., Read, Abigail, Li, Qiuning, Yu, Bing, Lee, Chih-Shia, Luo, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106784/
https://www.ncbi.nlm.nih.gov/pubmed/27891214
http://dx.doi.org/10.1186/s13578-016-0122-6