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One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation
BACKGROUND: The ability to transform normal human cells into cancer cells with the introduction of defined genetic alterations is a valuable method for understanding the mechanisms of oncogenesis. Easy establishment of immortalized but non-transformed human cells from various tissues would facilitat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106784/ https://www.ncbi.nlm.nih.gov/pubmed/27891214 http://dx.doi.org/10.1186/s13578-016-0122-6 |