Importins promote high-frequency NF-κB oscillations increasing information channel capacity

BACKGROUND: Importins and exportins influence gene expression by enabling nucleocytoplasmic shuttling of transcription factors. A key transcription factor of innate immunity, NF-κB, is sequestered in the cytoplasm by its inhibitor, IκBα, which masks nuclear localization sequence of NF-κB. In respons...

Descripción completa

Detalles Bibliográficos
Autores principales: Korwek, Zbigniew, Tudelska, Karolina, Nałęcz-Jawecki, Paweł, Czerkies, Maciej, Prus, Wiktor, Markiewicz, Joanna, Kochańczyk, Marek, Lipniacki, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106790/
https://www.ncbi.nlm.nih.gov/pubmed/27835978
http://dx.doi.org/10.1186/s13062-016-0164-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106790/
https://www.ncbi.nlm.nih.gov/pubmed/27835978
http://dx.doi.org/10.1186/s13062-016-0164-z

Ejemplares similares