Cargando…

Clinicopathological and prognostic significance of mTOR and phosphorylated mTOR expression in patients with esophageal squamous cell carcinoma: a systematic review and meta-analysis

BACKGROUND: Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase responsible for regulating ribosomal biogenesis and protein synthesis. Dysregulation of mTOR contributes to tumorigenesis, angiogenesis, cellular growth and metastasis but its roles in esophageal squamous cell carc...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shuangjiang, Wang, Zhiqiang, Huang, Jian, Cheng, Shan, Du, Heng, Che, Guowei, Peng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106813/
https://www.ncbi.nlm.nih.gov/pubmed/27835987
http://dx.doi.org/10.1186/s12885-016-2940-7