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A Penicillium chrysogenum-based expression system for the production of small, cysteine-rich antifungal proteins for structural and functional analyses

BACKGROUND: Small, cysteine-rich and cationic antifungal proteins (APs) from filamentous ascomycetes, such as NFAP from Neosartorya fischeri and PAF from Penicillium chrysogenum, are promising candidates for novel drug development. A prerequisite for their application is a detailed knowledge about t...

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Detalles Bibliográficos
Autores principales: Sonderegger, Christoph, Galgóczy, László, Garrigues, Sandra, Fizil, Ádám, Borics, Attila, Manzanares, Paloma, Hegedüs, Nikoletta, Huber, Anna, Marcos, Jose F., Batta, Gyula, Marx, Florentine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106836/
https://www.ncbi.nlm.nih.gov/pubmed/27835989
http://dx.doi.org/10.1186/s12934-016-0586-4