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A Penicillium chrysogenum-based expression system for the production of small, cysteine-rich antifungal proteins for structural and functional analyses
BACKGROUND: Small, cysteine-rich and cationic antifungal proteins (APs) from filamentous ascomycetes, such as NFAP from Neosartorya fischeri and PAF from Penicillium chrysogenum, are promising candidates for novel drug development. A prerequisite for their application is a detailed knowledge about t...
Autores principales: | Sonderegger, Christoph, Galgóczy, László, Garrigues, Sandra, Fizil, Ádám, Borics, Attila, Manzanares, Paloma, Hegedüs, Nikoletta, Huber, Anna, Marcos, Jose F., Batta, Gyula, Marx, Florentine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106836/ https://www.ncbi.nlm.nih.gov/pubmed/27835989 http://dx.doi.org/10.1186/s12934-016-0586-4 |
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