Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction

Objective. Clozapine provides a 50%–60% response rate in refractory schizophrenia but has a narrow therapeutic index and is susceptible to pharmacokinetic interactions, particularly with strong inhibitors or inducers of cytochrome P450 (CYP) 1A2. Case Report. We report the case of a 28-year-old nons...

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Detalles Bibliográficos
Autores principales: Meyer, Jonathan M., Proctor, George, Cummings, Michael A., Dardashti, Laura J., Stahl, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107233/
https://www.ncbi.nlm.nih.gov/pubmed/27872784
http://dx.doi.org/10.1155/2016/5606098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107233/
https://www.ncbi.nlm.nih.gov/pubmed/27872784
http://dx.doi.org/10.1155/2016/5606098

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