Cargando…

Ontogeny of human IgE‐expressing B cells and plasma cells

BACKGROUND: IgE‐expressing (IgE(+)) plasma cells (PCs) provide a continuous source of allergen‐specific IgE that is central to allergic responses. The extreme sparsity of IgE(+) cells in vivo has confined their study almost entirely to mouse models. OBJECTIVE: To characterize the development pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramadani, F., Bowen, H., Upton, N., Hobson, P. S., Chan, Y.‐C., Chen, J.‐B., Chang, T. W., McDonnell, J. M., Sutton, B. J., Fear, D. J., Gould, H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107308/
https://www.ncbi.nlm.nih.gov/pubmed/27061189
http://dx.doi.org/10.1111/all.12911