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Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment

All hematopoietic and immune cells are continuously generated by hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) through highly organized process of stepwise lineage commitment. In the steady state, HSCs are mostly quiescent, while HPCs are actively proliferating and contri...

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Detalles Bibliográficos
Autores principales: Kovtonyuk, Larisa V., Fritsch, Kristin, Feng, Xiaomin, Manz, Markus G., Takizawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107568/
https://www.ncbi.nlm.nih.gov/pubmed/27895645
http://dx.doi.org/10.3389/fimmu.2016.00502