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HER2-induced metastasis is mediated by AKT/JNK/EMT signaling pathway in gastric cancer

AIM: To investigated the relationships between HER2, c-Jun N-terminal kinase (JNK) and protein kinase B (AKT) with respect to metastatic potential of HER2-positive gastric cancer (GC) cells. METHODS: Immunohistochemistry was performed on tissue array slides containing 423 human GC specimens. Using H...

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Detalles Bibliográficos
Autores principales: Choi, Yiseul, Ko, Young San, Park, Jinju, Choi, Youngsun, Kim, Younghoon, Pyo, Jung-Soo, Jang, Bo Gun, Hwang, Douk Ho, Kim, Woo Ho, Lee, Byung Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107595/
https://www.ncbi.nlm.nih.gov/pubmed/27895401
http://dx.doi.org/10.3748/wjg.v22.i41.9141