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Hormonal Modulation of Breast Cancer Gene Expression: Implications for Intrinsic Subtyping in Premenopausal Women

Clinics are increasingly adopting gene-expression profiling to diagnose breast cancer subtype, providing an intrinsic, molecular portrait of the tumor. For example, the PAM50-based Prosigna test quantifies expression of 50 key genes to classify breast cancer subtype, and this method of classificatio...

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Detalles Bibliográficos
Autores principales: Bernhardt, Sarah M., Dasari, Pallave, Walsh, David, Townsend, Amanda R., Price, Timothy J., Ingman, Wendy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107819/
https://www.ncbi.nlm.nih.gov/pubmed/27896218
http://dx.doi.org/10.3389/fonc.2016.00241