Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ(12,14)-Prostaglandin J(2) (15d-PGJ(2)) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(−)FOXP3(+) Cells

The prostaglandin, 15-deoxy Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)), is a lipid mediator that plays an important role in the control of chronic inflammatory disease. However, the role of prostanoid in rheumatoid arthritis (RA) is not well determined. We demonstrated the therapeutic effect of 15d-PG...

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Detalles Bibliográficos
Autores principales: Carregaro, Vanessa, Napimoga, Marcelo H., Peres, Raphael S., Benevides, Luciana, Sacramento, Laís Amorim, Pinto, Larissa G., Grespan, Renata, Cunha, Thiago M., da Silva, João Santana, Cunha, Fernando Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107840/
https://www.ncbi.nlm.nih.gov/pubmed/27872515
http://dx.doi.org/10.1155/2016/9626427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107840/
https://www.ncbi.nlm.nih.gov/pubmed/27872515
http://dx.doi.org/10.1155/2016/9626427

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