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Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade

Mixed chimerism and tolerance can be successfully induced in rodents through allogeneic bone marrow transplantation (BMT) with costimulation blockade (CB), but varying success rates have been reported with distinct models and protocols. We therefore investigated the impact of minor antigen dispariti...

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Detalles Bibliográficos
Autores principales: Bigenzahn, Sinda, Pree, Ines, Klaus, Christoph, Pilat, Nina, Mahr, Benedikt, Schwaiger, Elisabeth, Nierlich, Patrick, Wrba, Friedrich, Wekerle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107841/
https://www.ncbi.nlm.nih.gov/pubmed/27872868
http://dx.doi.org/10.1155/2016/8635721