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Selenourea: a convenient phasing vehicle for macromolecular X-ray crystal structures

Majority of novel X-ray crystal structures of proteins are currently solved using the anomalous diffraction signal provided by selenium after incorporation of selenomethionine instead of natural methionine by genetic engineering methods. However, selenium can be inserted into protein crystals in the...

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Detalles Bibliográficos
Autor principal: Luo, Zhipu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107899/
https://www.ncbi.nlm.nih.gov/pubmed/27841370
http://dx.doi.org/10.1038/srep37123