Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα

In earlier studies, we showed that ATF4 down-regulation affects post-synaptic development and dendritic spine morphology in neurons through increased turnover of the Rho GTPase Cell Division Cycle 42 (Cdc42) protein. Here, we find that ATF4 down-regulation in both hippocampal and cortical neuron cul...

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Detalles Bibliográficos
Autores principales: Pasini, Silvia, Liu, Jin, Corona, Carlo, Peze-Heidsieck, Eugenie, Shelanski, Michael, Greene, Lloyd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107905/
https://www.ncbi.nlm.nih.gov/pubmed/27841340
http://dx.doi.org/10.1038/srep36952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107905/
https://www.ncbi.nlm.nih.gov/pubmed/27841340
http://dx.doi.org/10.1038/srep36952

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