11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes

Glucocorticoids are used to treat a number of human diseases but often lead to insulin resistance and metabolic syndrome. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. Despite the known...

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Detalles Bibliográficos
Autores principales: Peng, Kesong, Pan, Yong, Li, Jieli, Khan, Zia, Fan, Mendi, Yin, Haimin, Tong, Chao, Zhao, Yunjie, Liang, Guang, Zheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107914/
https://www.ncbi.nlm.nih.gov/pubmed/27841334
http://dx.doi.org/10.1038/srep37160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107914/
https://www.ncbi.nlm.nih.gov/pubmed/27841334
http://dx.doi.org/10.1038/srep37160

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