Didox and resveratrol sensitize colorectal cancer cells to doxorubicin via activating apoptosis and ameliorating P-glycoprotein activity

Doxorubicin (DOX) has limited efficacy in colorectal cancer due to multi-drug resistance. Resveratrol (RES) and didox (DID) are polyhydroxyphenols with potential chemosensitizing effects. Herein, we assessed the chemomodulatory effects of RES and DID to DOX in colorectal cancer cells. Equitoxic comb...

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Detalles Bibliográficos
Autores principales: Khaleel, Sahar A., Al-Abd, Ahmed M., Ali, Azza A., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107943/
https://www.ncbi.nlm.nih.gov/pubmed/27841296
http://dx.doi.org/10.1038/srep36855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107943/
https://www.ncbi.nlm.nih.gov/pubmed/27841296
http://dx.doi.org/10.1038/srep36855

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