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Single GDP-dissociation Inhibitor Protein regulates endocytic and secretory pathways in Leishmania

The role of GDP dissociation inhibitor (GDI) protein in regulation of Rab cycle in Leishmania is not known. Here, we have cloned and characterized the functions of GDI homologue in vivo in Leishmania. Our results have shown that LdGDI:WT along with GDP removes the Rab5 from purified endosomes and in...

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Detalles Bibliográficos
Autores principales: Shanmugam, Senthil kumar, Kumar, Kamal, Singh, Pawan Kishor, Rastogi, Ruchir, Mukhopadhyay, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107955/
https://www.ncbi.nlm.nih.gov/pubmed/27841328
http://dx.doi.org/10.1038/srep37058