Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex

Copper complexes with potent anti-tumor effect have been extensively developed. Most investigations of their modes of action focused on the biomolecular targets but not the signal transduction between target binding and cell death. We have previously shown that the cytotoxic complex pyridine(2,4-dih...

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Detalles Bibliográficos
Autores principales: Goh, Yan-Yih, Yan, Yaw-Kai, Tan, Nguan Soon, Goh, Su-Ann, Li, Shang, Teoh, You-Chuan, Lee, Peter P. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107956/
https://www.ncbi.nlm.nih.gov/pubmed/27841290
http://dx.doi.org/10.1038/srep36868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107956/
https://www.ncbi.nlm.nih.gov/pubmed/27841290
http://dx.doi.org/10.1038/srep36868

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