A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes

To better address the problem of drug resistance during cancer chemotherapy and explore the possibility of manipulating drug response phenotypes, we developed a network-based phenotype mapping approach (P-Map) to identify gene candidates that upon perturbed can alter sensitivity to drugs. We used ba...

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Detalles Bibliográficos
Autores principales: Cairns, Junmei, Ung, Choong Yong, da Rocha, Edroaldo Lummertz, Zhang, Cheng, Correia, Cristina, Weinshilboum, Richard, Wang, Liewei, Li, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107984/
https://www.ncbi.nlm.nih.gov/pubmed/27841317
http://dx.doi.org/10.1038/srep37003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107984/
https://www.ncbi.nlm.nih.gov/pubmed/27841317
http://dx.doi.org/10.1038/srep37003

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