5-azacytidine affects TET2 and histone transcription and reshapes morphology of human skin fibroblasts

Phenotype definition is controlled by epigenetic regulations that allow cells to acquire their differentiated state. The process is reversible and attractive for therapeutic intervention and for the reactivation of hypermethylated pluripotency genes that facilitate transition to a higher plasticity...

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Detalles Bibliográficos
Autores principales: Manzoni, Elena F. M., Pennarossa, Georgia, deEguileor, Magda, Tettamanti, Gianluca, Gandolfi, Fulvio, Brevini, Tiziana A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107985/
https://www.ncbi.nlm.nih.gov/pubmed/27841324
http://dx.doi.org/10.1038/srep37017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107985/
https://www.ncbi.nlm.nih.gov/pubmed/27841324
http://dx.doi.org/10.1038/srep37017

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