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5-azacytidine affects TET2 and histone transcription and reshapes morphology of human skin fibroblasts
Phenotype definition is controlled by epigenetic regulations that allow cells to acquire their differentiated state. The process is reversible and attractive for therapeutic intervention and for the reactivation of hypermethylated pluripotency genes that facilitate transition to a higher plasticity...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107985/ https://www.ncbi.nlm.nih.gov/pubmed/27841324 http://dx.doi.org/10.1038/srep37017 |