Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

Antibodies to citrullinated proteins, common in rheumatoid arthritis (RA) patients, are strongly associated to a specific set of HLA-DR alleles including HLA-DRB1*04:01, *04:04, and *01:01. Here, we first demonstrate that autoantibody levels toward the dominant citrullinated B cell epitope from α-en...

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Detalles Bibliográficos
Autores principales: Gerstner, Christina, Dubnovitsky, Anatoly, Sandin, Charlotta, Kozhukh, Genadiy, Uchtenhagen, Hannes, James, Eddie A., Rönnelid, Johan, Ytterberg, Anders Jimmy, Pieper, Jennifer, Reed, Evan, Tandre, Karolina, Rieck, Mary, Zubarev, Roman A., Rönnblom, Lars, Sandalova, Tatyana, Buckner, Jane H., Achour, Adnane, Malmström, Vivianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108039/
https://www.ncbi.nlm.nih.gov/pubmed/27895642
http://dx.doi.org/10.3389/fimmu.2016.00494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108039/
https://www.ncbi.nlm.nih.gov/pubmed/27895642
http://dx.doi.org/10.3389/fimmu.2016.00494

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