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Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats

Addiction is associated with neuroadaptive changes in the brain. In the present paper, we used a model of methamphetamine self-administration during which we used footshocks to divide rats into animals that continue to press a lever to get methamphetamine (shock-resistant) and those that significant...

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Detalles Bibliográficos
Autores principales: Cadet, Jean Lud, Krasnova, Irina N., Walther, Donna, Brannock, Christie, Ladenheim, Bruce, McCoy, Michael T., Collector, Daniel, Torres, Oscar V., Terry, Ndeah, Jayanthi, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108042/
https://www.ncbi.nlm.nih.gov/pubmed/27841313
http://dx.doi.org/10.1038/srep37002