Heparanase Released From Mesenchymal Stem Cells Activates Integrin beta1/HIF-2alpha/Flk-1 Signaling and Promotes Endothelial Cell Migration and Angiogenesis

Heparanase plays important roles in tumor angiogenesis. Our previous study demonstrated that hypoxic preconditioning (HPC) enhanced the angiogenic and therapeutic effects of mesenchymal stem cells (MSCs), effects that were paralleled by enhanced heparanase expression. This study was designed to eluc...

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Detalles Bibliográficos
Autores principales: Hu, Xinyang, Zhang, Ling, Jin, Jing, Zhu, Wei, Xu, Yinchuan, Wu, Yan, Wang, Yingchao, Chen, Han, Webster, Keith A., Chen, Huiqiang, Yu, Hong, Wang, Jian’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108061/
https://www.ncbi.nlm.nih.gov/pubmed/25754303
http://dx.doi.org/10.1002/stem.1995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108061/
https://www.ncbi.nlm.nih.gov/pubmed/25754303
http://dx.doi.org/10.1002/stem.1995

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