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Pharmacokinetics, toxicity, and cytochrome P450 modulatory activity of plumbagin
BACKGROUND: The antimalarial activity of plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), a naturally occurring naphthoquinone widely distributed in the Plumbaginaceae family has previously been demonstrated in vitro (good activity) and in vivo (weak activity). The aim of the study was to investig...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108082/ https://www.ncbi.nlm.nih.gov/pubmed/27839515 http://dx.doi.org/10.1186/s40360-016-0094-5 |